Clean Air and Containment Review
The journal to enhance your knowledge of cleanroom, clean air and containment technology
Editor: John Neiger
Publisher: Euromed Communications
Site design:
Fourwest Media
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Journal contents list

< Issue 36 | Issue 37

Issue 37: Winter/Spring 2019

Main features
Air quality indices and cleanroom ventilation equations, and their application in a cleanroom HVAC system, Part one: theoretical considerations
Shuji Chen, Andrew Butterworth, L. Jiang
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Abstract

This, the first part of a two-part paper summarizes current understanding of air quality indices and cleanroom ventilation equations and their use in a cleanroom heating, ventilation and air conditioning (HVAC) system. The equations for air quality indices, including the contaminant removal effectiveness index (CRE) and the air change effectiveness index (ACE) are reviewed, based on particles rather than gases, and dispersion rates from personnel and machinery are examined. The cleanroom ventilation equations, together with the air quality index and the dispersion rate of particles, are then used to calculate the minimum air change rate (ACR) that is required in non-unidirectional cleanrooms to achieve less than the maximum specified concentration of airborne particles. The second part of the paper will describe the experimental work carried out by EECO2 Ltd.

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Things that shouldn't happen in a cleanroom, and the consequences
Jim Polarine Jr, Beth Kroeger
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Abstract

This paper is an account of bad practices in cleanrooms, as observed by the authors. These bad practices are examined under the headings of personnel practices, operator behavior, aging facilities, items brought into cleanrooms and cleaning and disinfection failures. Examples include evidence of food being eaten in cleanrooms, SOPs stored on the cleanroom floor, post-it notes on cleanroom walls, gowning rooms crowded with supplies, horse-play, no differentiation of “clean” and “dirty” areas, a mouse seen in a cleanroom (!) and many more. A couple of FDA Warning Letters are quoted.

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Selection criteria for protective garments in cleanrooms and controlled environments
Steve Marnach
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Abstract

This document provides guidance on the selection criteria for protective cleanroom garments and accessories, and covers key selection principles valid for end users operating in cleanrooms and controlled environments within the Life Sciences, Pharmacy and Healthcare industries. Aspects, such as the required level of cleanliness, product and operator protection, fabric performance, garment lifecycle, regulatory requirements and documentation, traceability of garments and supply chain, provide valuable data, in order to assist end users in both the evaluation of the benefits and limitations of different cleanroom garment systems available on the market and in the selection of solutions suitable for different types of cleanroom applications.

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Standards
Recent cleanroom standards and changes to filter standards
John Neiger
Life-lines
News
Absolute Carbon Filters Ltd is your new carbon filters online solution
Pharminox Isolation Ltd. offers isolator training and equipment management
From paper to paperless: Tackling the 21CFR11 challenge with PMS
Ecolab Life Sciences offers proactive residue management for cleanrooms
Cherwell publishes guide on sterility testing
Pharma Clean Tech 2019, SNIEC Shanghai, June 18–20
Envair installs new stem cell isolator with integrated CO2 incubator in Taiwan
Steris Corporation announces addition of biofilm removal claim using ProKlenz®
Energy & Carbon Reduction Solutions introduces QASA© Quality Assured Scientific Approach to cleanroom energy optimisation
Events and Training courses